N-acylsphingosine galactosyltransferase EC#: 2.4.1.47; 凯望编码 (ChemWhat Code): 1377306

英文名 N-acylsphingosine galactosyltransferase
Example Structure Example Structure of N-acylsphingosine galactosyltransferase EC#: 2.4.1.47
别名 ceramide galactosyltransferase, cerebroside synthase, CGalT, CGT, galactosyltransferase, uridine diphosphogalactose-2-hydroxyacylsphingosine, galactosyltransferase, uridine diphosphogalactose-acylsphingosine, GALT, UDP galactose-N-acylsphingosine galactosyltransferase, UDPgalactose-2-hydroxyacylsphingosine galactosyltransferase, UDPgalactose:2-2-hydroxyacylsphingosine galactosyltransferase, UDPgalactose:ceramide galactosyltransferase, uridine diphosphogalactose-2-hydroxyacylsphingosine galactosyltransferase, uridine diphosphogalactose-acylsphingosine galactosyltransferase
EC Number 2.4.1.47
CAS编号 37277-56-8
Comments This membrane-bound, endoplasmic reticulum-located enzyme catalyses the last step in the synthesis of galactocerebrosides, which are abundant sphingolipids of the myelin membrane of the central nervous system and peripheral nervous system. It has a strong preference for ceramides that contain hydroxylated fatty acids. Formerly EC 2.4.1.45.
Cofactor
History
Reactions UDP-alpha-D-galactose + N-acylsphingosine = Udp + beta-D- galactosylceramide.

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