| 英文名 |
N-(long-chain-acyl)ethanolamine deacylase |
| Example Structure |
 |
| 别名 |
amidase, acylethanolamine, N-acylethanolamine acid amidase, N-acylethanolamine amidohydrolase, N-acylethanolamine-hydrolyzing acid amidase, N-acylethanolaminehydrolyzing acid amidase, NAAA, NAE-hydrolyzing acid amidase |
| EC Number |
3.5.1.60 |
| CAS编号 |
99283-61-1 |
| Comments |
This lysosomal enzyme acts best on palmitoyl ethanolamide, with lower activity on other?N-(long-chain-acyl)ethanolamines. It is only active at acidic pH. Unlike EC?3.5.1.99, fatty acid amide hydrolase, it does not act on primary amides such as oleamide, and has only a marginal activity with anandamide. The enzyme is translated as an inactive proenzyme, followed by autocatalytic cleavage into two subunits that reassociate to form an active heterodimeric complex. |
| Cofactor |
|
| History |
|
| Reactions |
N-(long-chain-acyl)ethanolamine + H(2)O = a long-chain carboxylate + ethanolamine. |
