| 别名 |
ARD homolog a, ARD1, ARD1-NAT1 Nalpha-acetyltransferase, ARD1131, ARD1198, ARD1225, ARD1235, ARD1p, arrest-defective protein 1, arrest-defective protein 1 homologue, DXS707, hNaa16p, hNat2, MUSE6, N-alpha-acetyltransferase 10, N-terminal protein acetyltransferase, NAA10, NAA10/ARD1, NAA15, Nalpha-acetyltransferase 10, NAT1, NatA, NatA acetyltransferase, NatA Nalpha-terminal acetyltransferase, NatA protein Nalpha-terminal-acetyltransferase complex, SSO0209, Ta0058, Ta1140, TE2, vnc |
| Comments |
N-terminal-acetylases (NATs) catalyse the covalent attachment of an acetyl moiety from acetyl-CoA to the free ¦Á-amino group at the N-terminus of a protein. This irreversible modification neutralizes the positive charge at the N-terminus and makes the N-terminal residue larger and more hydrophobic. The NatA complex is found in all eukaryotic organisms, and specifically targets N-terminal Ala, Gly, Cys, Ser, Thr, and Val residues, that became available after removal of the initiator methionine. Formerly EC 2.3.1.88. |
