nardilysin EC#: 3.4.24.61; 凯望编码 (ChemWhat Code): 1381056

英文名 nardilysin
Example Structure Example Structure of nardilysin EC#: 3.4.24.61
别名 hNRDc1, MGE, miniglucagon-generating endopeptidase, More, N-arginine dibasic (NRD) convertase, N-Arginine dibasic convertase, nardilysin, nardilysin (V8), nardilysin convertase, NRD convertase, NRD-convertase, Nrd1, NRDc
EC Number 3.4.24.61
CAS编号 157906-54-2
Comments Enzyme of 133 kDa from rat brain and testis. A homologue of pitrilysin containing the His-Phe-Leu-Glu-His zinc-binding sequence, and a highly acidic stretch of 71 residues. Unusually for a metalloendopeptidase, inhibited by bestatin, amastatin and?N-ethylmaleimide. In peptidase family?M16?(pitrilysin family).
Cofactor Zn2+
History
Reactions Hydrolysis of polypeptides, preferably at -Xaa-|-Arg-Lys-, and less commonly at -Arg-|-Arg-Xaa-, in which Xaa is not Arg or Lys.

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