| 英文名 |
nebramycin 5′ synthase |
| Example Structure |
 |
| 别名 |
obramycin carbamoyltransferase, TacA, TobZ |
| EC Number |
6.1.2.2 |
| CAS编号 |
|
| Comments |
Requires Fe(III). The enzyme from the bacterium?Streptoalloteichus tenebrarius?catalyses the activation of carbamoyl phosphate to?O-carbamoyladenylate and the subsequent carbamoylation of kanamycin and tobramycin. |
| Cofactor |
Fe3+ |
| History |
|
| Reactions |
(1) Tobramycin + carbamoyl phosphate + Atp + H(2)O = nebramycin 5′ + Amp + diphosphate + phosphate. (2) Kanamycin A + carbamoyl phosphate + atp + H(2)O = 6”-O- carbamoylkanamycin A + amp + diphosphate + phosphate. |
