| 英文名 |
nitric-oxide synthase (flavodoxin) |
| Example Structure |
 |
| 别名 |
bNOS, GK1676, nitric oxide synthetase, NO synthase, NOS, SANOS, YumC |
| EC Number |
1.14.14.47 |
| CAS编号 |
|
| Comments |
Binds heme (iron protoporphyrin IX) and tetrahydrobiopterin. The enzyme, found in bacteria and archaea, consist of only an oxygenase domain and functions together with bacterial ferredoxins or flavodoxins. The orthologous enzymes from plants and animals also contain a reductase domain and use only NADPH as the electron donor (cf. EC 1.14.13.39). |
| Cofactor |
ferriheme b;5,6,7,8-tetrahydrobiopterin |
| History |
|
| Reactions |
2 L-arginine + 3 reduced flavodoxin + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 oxidized flavodoxin + 4 H(2)O. |
