| 英文名 |
O-phospho-L-seryl-tRNA:Cys-tRNA synthase |
| Example Structure |
 |
| 别名 |
MJ1678, Sep-tRNA-Cys-tRNA synthase, Sep-tRNA:Cys-tRNA synthase, SepCysS |
| EC Number |
2.5.1.73 |
| CAS编号 |
1239229-21-0 |
| Comments |
In organisms like Archaeoglobus fulgidus lacking EC 6.1.1.16 (cysteine¡ªtRNA ligase) for the direct Cys-tRNACys formation, Cys-tRNACys is produced by an indirect pathway, in which EC 6.1.1.27 (O-phosphoseryl¡ªtRNA ligase) ligates O-phosphoserine to tRNACys, and EC 2.5.1.73 converts the produced O-phospho-L-seryl-tRNACys to Cys-tRNACys. The SepRS/SepCysS pathway is the sole route for cysteine biosynthesis in the organism [1]. Methanosarcina mazei can use both pathways, the direct route using EC 6.1.1.16 (cysteine¡ªtRNA ligase) and the indirect pathway with EC 6.1.1.27 (O-phosphoseryl-tRNA ligase) and EC 2.5.1.73 [2]. |
| Cofactor |
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| History |
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| Reactions |
O-phospho-L-seryl-tRNA(Cys) + sulfide = L-cysteinyl-tRNA(Cys) + phosphate. |
