| 英文名 |
oxepin-CoA hydrolase |
| Example Structure |
 |
| 别名 |
ECH-Aa, MaoC, oxepin-CoA hydrolase/3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase (NADP+), paaZ, PaaZ-ECH |
| EC Number |
3.3.2.12 |
| CAS编号 |
|
| Comments |
The enzyme from?Escherichia coli?is a bifunctional fusion protein that also catalyses EC?1.17.1.7, 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde dehydrogenase. Combined the two activities result in a two-step conversion of oxepin-CoA to 3-oxo-5,6-dehydrosuberyl-CoA, part of an aerobic phenylacetate degradation pathway [1,3,4]. The enzyme from?Escherichia coli?also exhibits enoyl-CoA hydratase activity utilizing crotonyl-CoA as a substrate [2]. |
| Cofactor |
|
| History |
|
| Reactions |
2-oxepin-2(3H)-ylideneacetyl-CoA + H(2)O = 3-oxo-5,6-dehydrosuberyl-CoA semialdehyde. |