| 英文名 |
phenol 2-monooxygenase (FADH2) |
| Example Structure |
 |
| 别名 |
FAD reductase, flavin reductase PheA2, PheA, PheA1, PheA2, phenol hydroxylase |
| EC Number |
1.14.14.20 |
| CAS编号 |
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| Comments |
The enzyme catalyses the ortho-hydroxylation of simple phenols into the corresponding catechols. It accepts 4-methylphenol, 4-chlorophenol, and 4-fluorophenol [1] as well as 4-nitrophenol, 3-nitrophenol, and resorcinol [3]. The enzyme is part of a two-component system that also includes an NADH-dependent flavin reductase. It is strictly dependent on FADH2 and does not accept FMNH2 [1,3]. cf. EC 1.14.13.7, phenol 2-monooxygenase (NADPH). |
| Cofactor |
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| History |
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| Reactions |
Phenol + FADH(2) + O(2) = catechol + Fad + H(2)O. |
