[phosphatase 2A protein]-leucine-carboxy methyltransferase EC#: 2.1.1.233; 凯望编码 (ChemWhat Code): 1376482
| 英文名 | [phosphatase 2A protein]-leucine-carboxy methyltransferase |
| Example Structure | ![]() |
| 别名 | C-terminal leucine protein carboxyl methyltransferase-1, LCMT-1, LCMT1, leucine carboxy methyltransferase-1, leucine carboxyl methyltransferase, leucine carboxyl methyltransferase 1, leucine carboxyl methyltransferase-1, leucine carboxylmethyltransferase-1, leucine carboxymethyltransferase 1/phosphatase methylesterase 1, phosphatase 2A protein methyltransferase, PP2A LCMT, PP2A methyltransferase, PP2A-specific methyltransferase, PPM1, Ppm1p, PPMT, protein phosphatase 2A leucine carboxyl methyltransferase, protein phosphatase methyltransferase 1 |
| EC Number | 2.1.1.233 |
| CAS编号 | |
| Comments | Methylates the C-terminal leucine of phosphatase 2A. A key regulator of protein phosphatase 2A. The methyl ester is hydrolysed by EC 3.1.1.89 (protein phosphatase methylesterase-1). Occurs mainly in the cytoplasm, Golgi region and late endosomes. |
| Cofactor | |
| History | |
| Reactions | S-adenosyl-L-methionine + [phosphatase 2A protein]-leucine = S-adenosyl- L-homocysteine + [phosphatase 2A protein]-leucine methyl ester. |
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![Example Structure of [phosphatase 2A protein]-leucine-carboxy methyltransferase EC#: 2.1.1.233](/wp-content/uploads/enzyme-structure/2.1.1.233.jpg)