phosphohistidine phosphatase EC#: 3.9.1.3; 凯望编码 (ChemWhat Code): 1381831

英文名 phosphohistidine phosphatase
Example Structure Example Structure of phosphohistidine phosphatase EC#: 3.9.1.3
别名 14 kDa phosphohistidine phosphatase, 14-kDa phosphohistidine phosphatase, 16 kDa protein histidine phosphatase, histidine protein phosphatase, phospho-histidine phosphatase, phosphohistidine phosphatase, phosphohistidine phosphatase 1, phosphohistidine phosphatase I, phosphopolyhistidine phosphatase, PHP, PHP14, PHPT-1, PHPT1, PHPTI, PP1, PP2A, protein histidine phosphatase, protein histidine phosphatase 1, protein-histidine phosphatase, SixA
EC Number 3.9.1.3
CAS编号
Comments This eukaryotic enzyme dephosphorylates phosphorylated histidine residues within proteins and peptides. The enzyme acts on phosphate groups attached to both the?pros- and?tele-nitrogen atoms, but the?pros- position is somewhat preferred (by a factor of two at the most) [4]. The substrate specificity depends on the amino acid sequence or structural context of the phosphohistidine in a phosphoprotein. The enzyme is also active on free phosphoramidate [1,4] and peptide-bound phospholysine [5].
Cofactor
History
Reactions A [protein]-N-phospho-L-histidine + H(2)O = a [protein]-L-histidine + phosphate.

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