phosphoinositide 5-phosphatase EC#: 3.1.3.36; 凯望编码 (ChemWhat Code): 1379443

英文名 phosphoinositide 5-phosphatase
Example Structure Example Structure of phosphoinositide 5-phosphatase EC#: 3.1.3.36
别名 (PI[4,5]P2) phosphatase, 5-ptase, 5PTase, 5ptase IV, 5PTase13, 72-5ptase, At5PTase7, Ci-VSP, Dd5P4, DGKeta, diphosphoinositide phosphatase, dOCRL, FRA3, I5P, inositol 1,4,5-trisphosphate 5-phosphatase, inositol 5′-phosphatase SHIP-2, inositol 5-phosphatase, inositol 5-phosphatase SHIP2, inositol lipid 5-phosphatase, inositol phosphatase, inositol polyphosphate 5-phosphatase, inositol polyphosphate 5-phosphatase 2, inositol polyphosphate 5-phosphatase7, inositol triphosphate 5-phosphomonoesterase, INP51, INPP5B, INPP5E, INPP5E 5-phosphatase, IP5P, IPP5C, IPPRp, lipid phosphatase SHIP2, Lowe’s oculocerebrorenal syndrome protein, More, OCRL, OCRL phosphatase, OCRL protein, OCRL1, OCRL1a, p150, phosphatase, triphosphoinositide, phosphatidyl 4,5-bisphosphate-specific phosphomonoesterase, phosphatidyl bisphosphate phosphatase, phosphatidyl-inositol 4,5-bisphosphate 5-phosphatase, phosphatidyl-myo-inositol-4,5-bisphosphate phosphatase, phosphatidyl-myo-inositol-4,5-bisphosphate phosphohydrolase, phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase, phosphatidylinositol 4,5-bisphosphate 5-phosphatase, phosphatidylinositol 4,5-bisphosphate phosphatase, phosphatidylinositol-4,5-bisphosphate 5-phosphatase, phosphatidylinositol-bisphosphatase, Phosphoinositide 5-phosphatase, phosphoinositide phosphatase, phosphoinositide-specific inositol polyphosphate 5-phosphatase IV, PI(4,5)P2 5-phosphatase, PI(4,5)P2 5-phosphatase A, PI(4,5)P2-5′-phosphatase, PIB5PA, PIP2 5-phosphatase, PIP2 phosphatase, PIP3 5-phosphatase, PIPP, proline-rich inositol polyphosphate 5-phosphatase, PtdIns(4,5)P2 5-phosphatase, PtdIns(4,5)P2 phosphatase, PtdIns(4;5)P2 5-phosphatase, PtdInsP3 5-phosphatase, rapamycin-inducible PI(4,5)P2 5-phosphatase, SAC-1, SAC9, SH2 domain containing inositol 5-phosphatase 2, SH2 domain containing inositol phosphatase 2, SH2-containing inositol 5′-phosphatase 2, SH2-containing inositol polyphosphate 5-phosphatase 2, SH2-domain containing inositol 5′-phosphatase, SHIP1, SHIP2, SigD, SJ-1, SJ1-145, SJ1-170, skeletal muscle and kidney enriched inositol phosphatase, skeletal muscle- and kidney-enriched inositol polyphosphate phosphatase, SKIP, SopB, SPsynaptojanin, Src homology 2 (SH2) domain-containing inositol-5-phosphatase 1, Src homology 2 domain containing inositol polyphosphate 5-phosphatase 2, Src homology 2-containing inositol 5-phosphatase 1, Synaptojanin, synaptojanin 1, synaptojanin-1, synaptojanin1, synaptojanin2, synj1, tb927.11.6270, triphosphoinositide phosphatase, triphosphoinositide phosphomonoesterase, type II 5PTase, type II diacylglycerol kinase eta, type II inositol polyphosphate 5-phosphatase, type II phosphoinositide 5-phosphatase, type IV phosphoinositide 5-phoshatase, Voltage-sensing phosphoinositide phosphatase, voltage-sensitive 5-phosphatase, voltage-sensitive phosphoinositide phosphatase Ci-VSP, VPA0450, VSP
EC Number 3.1.3.36
CAS编号 9036/1/5
Comments These enzymes can also remove the 5-phosphate from Ins(1,4,5)P3?and/or Ins(1,3,4,5)P4. They are a diverse family of enzymes, with differing abilities to catalyse two or more of the four reactions listed. They are thought to use inositol lipids rather than inositol phosphates as substrates?in vivo. All of them can use either or both of PtdIns(4,5)P2?and PtdIns(3,4,5)P3?as substrates; this is the main property that distinguishes them from EC?3.1.3.56, inositol-polyphosphate 5-phosphatase.
Cofactor
History
Reactions 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl- 1D-myo-inositol 4-phosphate + phosphate.

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