phosphoinositide phospholipase C EC#: 3.1.4.11; 凯望编码 (ChemWhat Code): 1379575

英文名 phosphoinositide phospholipase C
Example Structure Example Structure of phosphoinositide phospholipase C EC#: 3.1.4.11
别名 1-phosphatidyl-D-myo-inositol 4,5-bisphosphate inositoltrisphosphohydrolase, 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1, AtPLC1, AtPLC2, AtPLC3, AtPLC4, AtPLC5, AtPLC6, AtPLC7, AtPLC8, AtPLC9, Ca2 +-dependent phosphatidylinositol phosphodiesterase, calcium-ion-dependent phosphatidylinositol phosphodiesterase, cyclic phosphodiesterase, DsPLC2, endogenous phospholipase C, GDE2, GDPD5, glycerophosphodiester phosphodiesterase domain-containing 5a, glycerophosphodiester phosphodiesterase domain-containing 5b, glycosylphosphatidylinositol phospholipase C, GPI-PLC, GPI-specific phospholipase C, hPLC-eta, inositol phosphosphingolipid-phospholipase C, IPC-PLC, Isc1, low molecular weight PI-PLC, monophosphatidylinositol inositolphosphohydrolase, monophosphatidylinositol phosphodiesterase, More, mPLC-eta, myocardial phospholipase C, No receptor potential A protein, NorpA, PH-PLCdelta1, phosphatidylinosite-specific phospholipase C, phosphatidylinositide-specific phospholipase C, phosphatidylinositol -phospholipase C, phosphatidylinositol 4,5 bisphosphate-phospholipase C, phosphatidylinositol 4,5-bisphosphate phosphodiesterase, phosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase C, phosphatidylinositol specific phospholipase C, phosphatidylinositol-4,5-bisphosphate phosphodiesterase, phosphatidylinositol-4,5-bisphosphate phospholipase C, phosphatidylinositol-4,5-bisphosphate-specific phospholipase C, phosphatidylinositol-phosphodiesterase, phosphatidylinositol-phospholipase C, phosphatidylinositol-specific phospholipase, phosphatidylinositol-specific phospholipase C, phosphatidylinositol-specific phospholipase C-beta, phosphatidylinositol-specific phospholipase C1, phosphatidylinositol-specific phospholipase C2, phosphatidylinositol-specific phospholipase-C, phosphatidylinositol-specific phospholipases C, phosphodiesterase, phosphodiesterase, triphosphoinositide, phosphoinositidase C, phosphoinositide phospholipase C, phosphoinositide specific phospholipase C, phosphoinositide-phospholipase C, phosphoinositide-phospholipase C beta1, phosphoinositide-specific phospholipase, phosphoinositide-specific phospholipase C, phosphoinositide-specific phospholipase C 4, phosphoinositide-specific phospholipase C beta1, phosphoinositide-specific phospholipase C-zeta, phosphoinositide-specific phospholipase C2, phosphoinositide-specific phospholipase-Cgamma, phosphoinositide-specific phospholipases C, phospholipase C, phospholipase C 1, phospholipase C beta1, phospholipase C beta3, phospholipase C epsilon, phospholipase C zeta, phospholipase C-beta 2, phospholipase C-beta-1, phospholipase C-beta1, phospholipase C-beta2, phospholipase C-beta3, phospholipase C-delta-1, phospholipase C-delta1, phospholipase C-epsilon, phospholipase C-eta, phospholipase C-eta1a, phospholipase C-eta1b, phospholipase C-eta1c, phospholipase C-gamma1, phospholipase C-gamma2, phospholipase C-like phosphodiesterase, phospholipase Cbeta1, phospholipase Cepsilon, phospholipase Cgamma1, phospholipase Cgamma2, phosphotidylinositol 4,5-bisphosphate-specific phospholipase C, PI-PLC, PI-PLC beta 1, PI-PLC beta1, PI-PLC beta3, PI-PLC beta4, PI-PLC delta1, PI-PLC delta3, PI-PLC delta4, PI-PLC epsilon, PI-PLC gamma1, PI-PLC gamma2, PI-PLC-beta1, PI-PLC-?1, PI-PLC1, PI-PLCbeta, PI-PLCbeta1, PI-PLCbeta2, PI-PLCbeta3, PI-PLCbeta4, PI-PLCc, PI-PLCdelta1, PI-PLCdelta3, PI-PLCepsilon, PI-PLCeta, PI-PLCgamma, PI-PLCgamma1, PI-PLCm, PI-PLCzeta, PI-specific phospholipase C, PIC, PIP(2)-specific-phospholipase, PIP2 PDE, PIP2 phosphodiesterase, PIP2-phospholipase C, PIP2-PLC, PIP2-specific phospholipase C, PIPLC, PL-C, PLC, PLC beta1, PLC beta1b, PLC beta3, PLC delta1, PLC epsilon, PLC epsilon1a, PLC epsilon1b, PLC gamma1, PLC zeta, PLC-148, PLC-154, PLC-21, PLC-85, PLC-beta, PLC-beta-1, PLC-beta1b, PLC-beta2, PLC-delta, PLC-delta-1, PLC-delta1, PLC-deltasu, PLC-epsilon, PLC-eta, PLC-eta1, PLC-eta2, PLC-gamma, PLC-gamma1, PLC-gamma2, PLC-I, PLC-II, PLC-zeta, PLC1, Plc1p, PLC2, PLC3, PLC4, PLC5, PLC6, plcA, PLCbeta1, PLCbeta2, PLCbeta3, PLCbeta4, PLCdelta1, PLCdelta3, PLCdelta4, PLCdeta1, PLCepsilon, PLCeta1, PLCeta2, PLCgamma, PLCgamma1, PLCgamma2, pleckstrin homology-phospholipase C-delta1, polyphosphoinositide phospholipase C, PsPLC, PtdIns phosphodiesterase, PtdIns(4,5)P2-directed phospholipase C, PtdIns(4,5)P2-PLC, suPLCbeta, TcPI-PLC, TgPI-PLC, triphosphoinositide phosphodiesterase, Vr-PLC1, Vr-PLC2, Vr-PLC3, Vr-PLC3 protein, ZmPLC1
EC Number 3.1.4.11
CAS编号 37213-51-7
Comments These enzymes form some of the cyclic phosphate Ins(cyclic 1,2)P(4,5)P2?as well as Ins(1,4,5)P3. They show activity towards phosphatidylinositol, i.e., the activity of EC?4.6.1.13, phosphatidylinositol diacylglycerol-lyase,?in vitro?at high [Ca2+]. Four ¦Â-isoforms regulated by G-proteins, two ¦Ã-forms regulated by tyrosine kinases, four ¦Ä-forms regulated at least in part by calcium and an ¦Å-form, probably regulated by the oncogene ras, have been found.
Cofactor
History
Reactions 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.

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