physarolisin EC#: 3.4.21.103; 凯望编码 (ChemWhat Code): 1380641

英文名 physarolisin
Example Structure Example Structure of physarolisin EC#: 3.4.21.103
别名 EC 3.4.23.27, EC 3.4.23.6, physarolisin, physarolisin I, physarolysin II, Physarum aspartic proteinase, proteinase, Dictyostelium discoideum aspartic, proteinase, Dictyostelium discoideum aspartic, E, proteinase, Physarum flavicomum aspartic, proteinase, Physarum polycephalum acid
EC Number 3.4.21.103
CAS编号 94949-28-7
Comments Belongs in peptidase family?S53. From the slime mold?Physarum polycephalum. Is not inhibited by pepstatin, but is blocked by methyl 2-diazoacetamidohexanoate. Closely similar enzymes are found in?Dictyostelium discoideum?and?P. flavicomum. Formerly included in EC?3.4.23.6.
Cofactor
History
Reactions Milk clotting activity. Preferential cleavage of 8-Gly-|-Ser-9 in B chain of insulin most rapidly, followed by 11-Leu-|-Val-12, 19-Cys(SO(3)H)-|-Gly and 24-Phe-|-Phe-25. No action on Ac-Phe-Tyr(I)(2).

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