| 英文名 |
pimelyl-[acyl-carrier protein] methyl ester esterase |
| Example Structure |
![Example Structure of pimelyl-[acyl-carrier protein] methyl ester esterase EC#: 3.1.1.85](/wp-content/uploads/enzyme-structure/3.1.1.85.jpg) |
| 别名 |
BioG, BioH, BioH protein, pimeloyl-ACP methyl esterase |
| EC Number |
3.1.1.85 |
| CAS编号 |
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| Comments |
Involved in biotin biosynthesis in Gram-negative bacteria. The enzyme exhibits carboxylesterase activity, particularly toward substrates with short acyl chains [1,2]. Even though the enzyme can interact with coenzyme A thioesters [3], the in vivo role of the enzyme is to hydrolyse the methyl ester of pimeloyl-[acyl carrier protein], terminating the part of the biotin biosynthesis pathway that is catalysed by the fatty acid elongation enzymes [4]. |
| Cofactor |
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| History |
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| Reactions |
Pimeloyl-[acyl-carrier protein] methyl ester + H(2)O = pimeloyl-[acyl- carrier protein] + methanol. |
