prostaglandin-E2 9-reductase EC#: 1.1.1.189 • ChemWhat中文网

prostaglandin-E2 9-reductase EC#: 1.1.1.189; 凯望编码 (ChemWhat Code): 1373253


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英文名	prostaglandin-E2 9-reductase
Example Structure
别名	20-alpha-HSD, 20-alpha-hydroxysteroid dehydrogenase, 9-keto-prostaglandin E2 reductase, 9-ketoprostaglandin reductase, 9-KPR, CBR1, More, mPGES, PG 9-ketoreductase/carbonyl reductase, PGE 9-ketoreductase, PGE2 9-ketoreductase, PGE2-9-K, PGE2-9-ketoreductase, PGE2-9-OR, prostaglandin 9-ketoreductase, prostaglandin 9-ketoreductase/carbonyl reductase, prostaglandin E 9-ketoreductase, prostaglandin E2 9-ketoreductase, prostaglandin E2-9-oxoreductase, prostaglandin-E2 9-keto reductase, reductase, 15-hydroxy9-oxoprostaglandin
EC Number	1.1.1.189
CAS编号	42613-35-4
Comments	Reduces prostaglandin E2 to prostaglandin F2¦Á. A number of other 9-oxo- and 15-oxo-prostaglandin derivatives can also be reduced to the corresponding hydroxy compounds. May be identical with EC 1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+).
Cofactor
History
Reactions	(5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP(+) = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + Nadph.