protein-glutamine gamma-glutamyltransferase EC#: 2.3.2.13; 凯望编码 (ChemWhat Code): 1377162

英文名 protein-glutamine gamma-glutamyltransferase
Example Structure Example Structure of protein-glutamine gamma-glutamyltransferase EC#: 2.3.2.13
别名 BmTGA, chloroplast transglutaminase, chlTGase, factor XIII, factor XIIIa, fibrin stabilizing factor, fibrinoligase, glutamine:amine gamma-glutamyl-transferase, glutaminylpeptide gamma-glutamyltransferase, glutamyltransferase, glutaminylpeptide gamma-, Laki-Lorand factor, microbial transglutaminase, MTG, MTGase, polyamine transglutaminase, protein-glutamine gamma-glutamyltransferase, R-glutaminyl-peptide:amine gamma-glutamyl transferase, STG I, TG-2, TG1, TG2, TG3, TG4, TG5, TG6, tGA, TGase, TGase 2, Tgase 3, Tgase II, TGase-2, TGase2, TGB, TGK1, TGK2, TGL, TGM2, TGZ, tissue transglutaminase, tissue transglutaminase 2, transglutaminase, transglutaminase 2, transglutaminase 3, transglutaminase 6, transglutaminase C, transglutaminase factor XIII, transglutaminase type II, transglutaminase-2, transglutaminase2, tTG, tTG-2, type I transglutaminase, type-2 transglutaminase
EC Number 2.3.2.13
CAS编号 80146-85-6
Comments Requires Ca2+. The ¦Ã-carboxamide groups of peptide-bound glutamine residues act as acyl donors, and the 6-amino-groups of protein- and peptide-bound lysine residues act as acceptors, to give intra- and inter-molecular N6-(5-glutamyl)-lysine cross-links. Formed by proteolytic cleavage from plasma Factor XIII.
Cofactor Ca2+
History
Reactions A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)- (gamma-glutamyl)-L-lysine cross-link + NH(3).

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