| 英文名 |
protein N-terminal monomethyltransferase |
| Example Structure |
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| 别名 |
METTL11B, N-terminal monomethylase, NRMT2 |
| EC Number |
2.1.1.299 |
| CAS编号 |
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| Comments |
This enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal. |
| Cofactor |
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| History |
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| Reactions |
S-adenosyl-L-methionine + N-terminal-(A,P,S)PK-[protein] = S-adenosyl-L- homocysteine + N-terminal-N-methyl-N-(A,P,S)PK-[protein]. |
