protein O-GlcNAcase EC#: 3.2.1.169 • ChemWhat中文网

protein O-GlcNAcase EC#: 3.2.1.169; 凯望编码 (ChemWhat Code): 1380083


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英文名	protein O-GlcNAcase
Example Structure
别名	beta-N-acetylglucosaminidase, BtGH84, CP40, CpNagJ, CpOGA, cytoplasmic O-GlcNAcase, endo-beta-N-acetylglucosaminidase, EndoS-like endoglycosidase, glycoside hydrolase O-GlcNAcase, hexosaminidase, hOGA, mNCOAT, NagJ, NCOAT, neutral hexosaminidase C, neutral O-GlcNAcase, O-GlcNAc hydrolase, O-GlcNAc selective N-acetyl-beta-D-glucosaminidase, O-GlcNAc specific beta-N-acetylglucosaminidase, O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase, O-GlcNAc-selective-N-acetyl-beta-D-glucosaminidase, O-GlcNAcase, O-linked beta-N-acetyl glucosaminase, O-linked N-acetylglucosaminase, OGA, OGA-FL, OGA-NV
EC Number	3.2.1.169
CAS编号
Comments	Within higher eukaryotes post-translational modification of protein serines/threonines with?N-acetylglucosamine (O-GlcNAc) is dynamic, inducible and abundant, regulating many cellular processes by interfering with protein phosphorylation.?O-GlcNAc transferase (EC?2.4.1.155) transfers GlcNAc onto substrate proteins and?O-GlcNAcase (EC?3.2.1.169) cleaves GlcNAc from the modified proteins.
Cofactor
History
Reactions	(1) [Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-serine + H(2)O = [protein]-L-serine + N-acetyl-D-glucosamine. (2) [Protein]-3-O-(N-acetyl-beta-D-glucosaminyl)-L-threonine + H(2)O = [protein]-L-threonine + N-acetyl-D-glucosamine.