protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase EC#: 2.4.1.313; 凯望编码 (ChemWhat Code): 1377648

英文名 protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase
Example Structure Example Structure of protein O-mannose beta-1,3-N-acetylgalactosaminyltransferase EC#: 2.4.1.313
别名 B3GALNT2, beta 1,3-N-acetylgalactosaminyltransferase2, beta-1,3-N-acetylgalactosaminyltransferase 2, beta1,3-N-acetylgalactosaminyltransferase II, beta1,3-N-acetylgalactosaminyltransferase-II, beta3GalNAc-T2, UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2
EC Number 2.4.1.313
CAS编号
Comments The human protein is specific for UDP-N-acetyl-¦Á-D-galactosamine as donor [1]. The enzyme is involved in the formation of a phosphorylated trisaccharide on a threonine residue of ¦Á-dystroglycan, an extracellular peripheral glycoprotein that acts as a receptor for extracellular matrix proteins containing laminin-G domains.
Cofactor
History
Reactions UDP-N-acetyl-alpha-D-galactosamine + 3-O-(N-acetyl-beta-D-glucosaminyl- (1->4)-alpha-D-mannosyl)-L-threonyl-[protein] = Udp + 3-O-(N-acetyl-beta- D-galactosaminyl-(1->3)-N-acetyl-beta-D-glucosaminyl-(1->4)-alpha-D- mannosyl)-L-threonyl-[protein].

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