pyrimidodiazepine synthase EC#: 1.5.4.1; 凯望编码 (ChemWhat Code): 1374465

英文名 pyrimidodiazepine synthase
Example Structure Example Structure of pyrimidodiazepine synthase EC#: 1.5.4.1
别名 More, PDA synthase
EC Number 1.5.4.1
CAS编号 93586-06-2
Comments In the reverse direction of reaction, the reduction of 6-pyruvoyl-tetrahydropterin is accompanied by the opening of the 6-membered pyrazine ring and the formation of the 7-membered diazepine ring. The pyrimidodiazepine involved is an acetyldihydro derivative. Involved in the formation of the eye pigment drosopterin in Drosophila melanogaster.
Cofactor
History
Reactions 2-amino-6-acetyl-3,7,8,9-tetrahydro-3H-pyrimido(4,5-b)[1,4]diazepin-4-one + glutathione disulfide + H(2)O = 6-pyruvoyltetrahydropterin + 2 glutathione.

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