| 英文名 |
rRNA small subunit pseudouridine methyltransferase Nep1 |
| Example Structure |
 |
| 别名 |
Bowen-Conradi syndrome protein, Emg1, Emg1p, essential for mitotic growth 1, N1-specific pseudouridine methyltransferase, Nep1, Nep1 methyltransferase, Nep1p, nucleolar essential protein 1, pseudouridine N1-methyltransferase, pseudouridine-N1-specific methyltransferase |
| EC Number |
2.1.1.260 |
| CAS编号 |
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| Comments |
This enzyme, which occurs in both prokaryotes and eukaryotes, recognizes specific pseudouridine residues (¦·) in small subunits of ribosomal RNA based on the local RNA structure. It recognizes ¦·914 in 16S rRNA from the archaeon Methanocaldococcus jannaschii, ¦·1191 in yeast 18S rRNA, and ¦·1248 in human 18S rRNA. |
| Cofactor |
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| History |
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| Reactions |
S-adenosyl-L-methionine + pseudouridine(1191) in yeast 18S rRNA = S-adenosyl-L-homocysteine + N(1)-methylpseudouridine(1191) in yeast 18S rRNA. |
