sanguinarine reductase EC#: 1.3.1.107; 凯望编码 (ChemWhat Code): 1374085

英文名 sanguinarine reductase
Example Structure Example Structure of sanguinarine reductase EC#: 1.3.1.107
别名 SARED1
EC Number 1.3.1.107
CAS编号
Comments The enzyme, purified from the California poppy (Eschscholzia californica), is involved in detoxifying the phytoalexin sanguinarine produced by poppy itself (cf. EC 1.5.3.12, dihydrobenzophenanthridine oxidase), when it binds to the cell wall of the poppy cell. The reaction with NADPH is up to three times faster than that with NADH at low concentrations (<10 uM) of the dinucleotide. At higher concentrations the reaction with NADPH is inhibited but not that with NADH [1].
Cofactor
History
Reactions (1) Dihydrosanguinarine + NAD(P)(+) = sanguinarine + NAD(P)H. (2) Dihydrochelirubine + NAD(P)(+) = chelirubine + NAD(P)H.

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