sedolisin EC#: 3.4.21.100 • ChemWhat中文网 | 凯望化学与生物数据库

sedolisin EC#: 3.4.21.100; 凯望编码 (ChemWhat Code): 1380636


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英文名	sedolisin
Example Structure
别名	EC 3.4.23.37, grifolisin, PCP, Pepstatin-insensitive carboxyl proteinase, PSCP, pseudomonalisin, pseudomonapepsin, Pseudomonas serine-carboxyl proteinase, Pseudomonas sp. pepstatin-insensitive carboxyl proteinase, scytalidolisin, scytalidopepsin A, SedA, SedB, SedC, SedD, sedolisin
EC Number	3.4.21.100
CAS编号
Comments	An enzyme secreted by?Pseudomonas?sp. No. 101. Optimum pH is 4. It is distinguished from EC?3.4.21.101, xanthomonalisin, by its insensitivity to EPNP and from EC?3.4.23.31, scytalidopepsin B, by this property and by its unrelated amino-acid sequence. Inhibited by tyrostatin, a peptide aldehyde [2]. Type example of peptidase family?S53.
Cofactor
History
Reactions	Hydrolysis of the B chain of insulin at 13-Glu-\|-Ala-14, 15-Leu-\|-Tyr-16 and 25-Phe-\|-Tyr-26 and angiotensin I at 4-Tyr-\|-Ile-5. A good synthetic substrate is Lys-Pro-Ile-Glu-Phe-\|-Phe(NO(2))-Arg-Leu.