| 别名 |
17beta-hydroxysteroid dehydrogenase type 10, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl CoA reductase, ACADS, Acfer_0556, Acfer_1477, acyl-CoA dehydrogenase short chain, BCAD, BCD, bcd2, BcdAf, bSCAD, butyryl CoA dehydrogenase, butyryl coenzyme A dehydrogenase, butyryl-CoA dehydrogenase, butyryl-CoA dehydrogenase complex, butyryl-CoA dehydrogenase/Etf complex, CD1054, dehydrogenase, butyryl coenzyme A, EC 1.3.2.1, enoyl-coenzyme A reductase, ethylene reductase, HADHSC, HADII, HSD10, MHBD, non-dissociating bifurcating Etf-Bcd complex, SCAD, ScdA, SCHAD, short chain 3-hydroxyacyl-CoA dehydrogenase, short chain acyl-CoA dehydrogenase, short-chain 3-hydroxyacyl-CoA dehydrogenase, short-chain acyl CoA dehydrogenase, short-chain acyl-CoA dehydrogenase, short-chain acyl-coenzyme A dehydrogenase, short-chain acylCoA dehydrogenase, type II 3-hydroxyacyl-CoA dehydrogenase, unsaturated acyl coenzyme A reductase |
| Comments |
Contains FAD as prosthetic group. One of several enzymes that catalyse the first step in fatty acids ¦Â-oxidation. The enzyme catalyses the oxidation of saturated short-chain acyl-CoA thioesters to give a trans 2,3-unsaturated product by removal of the two pro-R hydrogen atoms. The enzyme from beef liver accepts substrates with acyl chain lengths of 3 to 8 carbon atoms. The highest activity was reported with either butanoyl-CoA [2] or pentanoyl-CoA [4]. The enzyme from rat has only 10% activity with hexanoyl-CoA (compared to butanoyl-CoA) and no activity with octanoyl-CoA [6]. cf. EC 1.3.8.7, medium-chain acyl-CoA dehydrogenase, EC 1.3.8.8, long-chain acyl-CoA dehydrogenase, and EC 1.3.8.9, very-long-chain acyl-CoA dehydrogenase. |
