| 别名 |
hK7, HSCCE, human stratum corneum chymotryptic enzyme, K7, kallikrein 7, kallikrein-7, kallikrein-related peptidase, kallikrein-related peptidase 7, KLK7, More, S01.300, SCCE, stratum corneum chymotryptic enzyme, tissue kallikrein, tissue kallikrein 7 |
| Comments |
This enzyme has wide substrate specificity, being able to degrade heat-denatured bovine casein and the ¦Á-chain of native human fibrinogen. It cleaves the B chain of bovine insulin at Leu6©àCya7, Tyr16©àLeu17, Phe25©àTyr26?and Tyr26©àThr27?[1]. It is thought to play a role in the desquamation (skin-shedding) of the outer layer of skin, the stratum corneum, by degrading intercellular cohesive structures [1,2]. Belongs in peptidase family?S1A. |
