| Comments |
Requires Co2+?for maximal activity [1].?N2-Acetylglutamate is not a substrate. This is the final enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC?2.3.1.109?(arginine?N-succinyltransferase), EC?3.5.3.23?(N-succinylarginine dihydrolase), EC?2.6.1.11?(acetylornithine transaminase), EC?1.2.1.71?(succinylglutamate-semialdehyde dehydrogenase) and EC?3.5.1.96?(succinylglutamate desuccinylase). |
