| 英文名 |
succinylglutamate-semialdehyde dehydrogenase |
| Example Structure |
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| 别名 |
aruD, AstD, N-succinylglutamate 5-semialdehyde dehydrogenase, SGSD, succinic semialdehyde dehydrogenase, succinylglutamic semialdehyde dehydrogenase |
| EC Number |
1.2.1.71 |
| CAS编号 |
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| Comments |
This is the fourth enzyme in the arginine succinyltransferase (AST) pathway for the catabolism of arginine [1]. This pathway converts the carbon skeleton of arginine into glutamate, with the concomitant production of ammonia and conversion of succinyl-CoA into succinate and CoA. The five enzymes involved in this pathway are EC 2.3.1.109 (arginine N-succinyltransferase), EC 3.5.3.23 (N-succinylarginine dihydrolase), EC 2.6.1.11 (acetylornithine transaminase), EC 1.2.1.71 (succinylglutamate-semialdehyde dehydrogenase) and EC 3.5.1.96 (succinylglutamate desuccinylase) [3,6]. |
| Cofactor |
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| History |
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| Reactions |
N-succinyl-L-glutamate 5-semialdehyde + NAD(+) + H(2)O = N-succinyl-L- glutamate + Nadh. |
