| 英文名 |
taurine-pyruvate aminotransferase |
| Example Structure |
 |
| 别名 |
aminotransferase, taurine-pyruvate, HPA, hypotaurine-inducible hypotaurine:pyruvate aminotransferase, Pden_4273, taurine transaminase, taurine:pyruvate aminotransferase, tPA |
| EC Number |
2.6.1.77 |
| CAS编号 |
|
| Comments |
The enzyme from?Bilophila wadsworthia?requires pyridoxal 5′-phosphate as a cofactor, and catalyses a reversible reaction that starts an anaerobic taurine degradation pathway. ¦Â-Alanine is also a significant amino group donor. The enzyme from the bacterium?Pseudomonas denitrificans?PD1222 can also use hypotaurine, producing 2-sulfinoacetaldehyde, which spontaneously hydrolyses to sulfite and acetaldehyde. Unlike EC?2.6.1.55, taurine¡ª2-oxoglutarate transaminase, 2-oxoglutarate cannot serve as an acceptor for the amino group. |
| Cofactor |
pyridoxal 5′-phosphate |
| History |
|
| Reactions |
Taurine + pyruvate = L-alanine + 2-sulfoacetaldehyde. |
