| 英文名 |
tRNA (cytidine32/uridine32-2′-O)-methyltransferase |
| Example Structure |
 |
| 别名 |
Saci_0621, TrMet(Xm32), TrmJ, tRNA:Cm32/Um32 methyltransferase, YfhQ |
| EC Number |
2.1.1.200 |
| CAS编号 |
|
| Comments |
In Escherichia coli TrmJ is the only methyltransferase responsible for the formation of 2′-O-methylcytidine32 in tRNA. No methylation of cytosine34 in tRNALeu(CAA). In vitro the enzyme 2′-O-methylates cytidine34 of tRNASer1 and uridine32 of tRNAGln2. |
| Cofactor |
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| History |
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| Reactions |
(1) S-adenosyl-L-methionine + cytidine(32) in tRNA = S-adenosyl-L- homocysteine + 2′-O-methylcytidine(32) in tRNA. (2) S-adenosyl-L-methionine + uridine(32) in tRNA = S-adenosyl-L- homocysteine + 2′-O-methyluridine(32) in tRNA. |
