tyrosine phenol-lyase EC#: 4.1.99.2; 凯望编码 (ChemWhat Code): 1382191

英文名 tyrosine phenol-lyase
Example Structure Example Structure of tyrosine phenol-lyase EC#: 4.1.99.2
别名 beta-tyrosinase, Fn-TPL, L-tyrosine phenol-lyase, phenol-lyase, tyrosine, TnaA, TPL, tyrosine phenol lyase, tyrosine phenol-lyase, tyrosine-phenol lyase
EC Number 4.1.99.2
CAS编号 9059-31-8
Comments A pyridoxal-phosphate protein. The enzyme cleaves a carbon-carbon bond, releasing phenol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. The latter reaction, which can occur spontaneously, can also be catalysed by EC?3.5.99.10, 2-iminobutanoate/2-iminopropanoate deaminase. The enzyme also slowly catalyses similar reactions with?D-tyrosine,?S-methyl-L-cysteine,?L-cysteine,?L-serine and?D-serine.
Cofactor pyridoxal 5′-phosphate
History
Reactions L-tyrosine + H(2)O = phenol + pyruvate + NH(3).

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