| 英文名 |
tyrosine phenol-lyase |
| Example Structure |
 |
| 别名 |
beta-tyrosinase, Fn-TPL, L-tyrosine phenol-lyase, phenol-lyase, tyrosine, TnaA, TPL, tyrosine phenol lyase, tyrosine phenol-lyase, tyrosine-phenol lyase |
| EC Number |
4.1.99.2 |
| CAS编号 |
9059-31-8 |
| Comments |
A pyridoxal-phosphate protein. The enzyme cleaves a carbon-carbon bond, releasing phenol and an unstable enamine product that tautomerizes to an imine form, which undergoes a hydrolytic deamination to form pyruvate and ammonia. The latter reaction, which can occur spontaneously, can also be catalysed by EC?3.5.99.10, 2-iminobutanoate/2-iminopropanoate deaminase. The enzyme also slowly catalyses similar reactions with?D-tyrosine,?S-methyl-L-cysteine,?L-cysteine,?L-serine and?D-serine. |
| Cofactor |
pyridoxal 5′-phosphate |
| History |
|
| Reactions |
L-tyrosine + H(2)O = phenol + pyruvate + NH(3). |