U6 snRNA m6A methyltransferase EC#: 2.1.1.346; 凯望编码 (ChemWhat Code): 1376632
| 英文名 | U6 snRNA m6A methyltransferase |
| Example Structure |  |
| 别名 | methyltransferase like protein 16, METTL16, N6-methyladenosine (m6A) methyltransferase |
| EC Number | 2.1.1.346 |
| CAS编号 | |
| Comments | This enzyme, found in vertebrates, methylates a specific adenine in a hairpin structure of snRNA. The effects of the binding of the methyltransferase to its substrate is important for the regulation of the activity of an isoform of EC 2.5.1.6, methionine adenosyltransferase, that produces S-adenosyl-L-methionine [1,2]. The enzyme also binds (and maybe methylates) the lncRNAs XIST and MALAT1 as well as a number of pre-mRNAs at specific positions often found in the intronic regions [2]. |
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