undecaprenyl-diphosphooligosaccharide-protein glycotransferase EC#: 2.4.99.19; 凯望编码 (ChemWhat Code): 1377865

英文名 undecaprenyl-diphosphooligosaccharide-protein glycotransferase
Example Structure Example Structure of undecaprenyl-diphosphooligosaccharide-protein glycotransferase EC#: 2.4.99.19
别名 bacterial oligosaccharyltransferase, bacterial OST, N-oligosaccharyltransferase, N-OTase, oligosaccharyl transferase, oligosaccharyltransferase, oligosacharyltransferase, OST, OT, OTase, PglB, PglB1, PglB2
EC Number 2.4.99.19
CAS编号
Comments A bacterial enzyme that has been isolated from Campylobacter jejuni [1] and Campylobacter lari [2]. It forms a glycoprotein by the transfer of a glucosyl-N-acetylgalactosaminyl-N,N’-diacetylbacillosamine (GalNAc2(Glc)GalNAc3diNAcBac) polysaccharide and related oligosaccharides to the side-chain of an L-asparagine residue in the sequence -Asp/Glu-Xaa-Asn-Xaa’-Ser/Thr- (Xaa and Xaa’ not Pro) in nascent polypeptide chains. Requires Mn2+ or Mg2+. Occurs on the external face of the plasma membrane. The polyprenol involved is normally tritrans,heptacis-undecaprenol but a decaprenol is used by some species.
Cofactor Mn2+ or Mg2+
History
Reactions Tritrans,heptacis-undecaprenyl diphosphooligosaccharide + [protein]-L- asparagine = tritrans,heptacis-undecaprenyl diphosphate + a glycoprotein with the oligosaccharide chain attached by N-beta-D-glycosyl linkage to protein L-asparagine.

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