| 英文名 |
unsaturated chondroitin disaccharide hydrolase |
| Example Structure |
 |
| 别名 |
Phep_2238, Phep_2649, Phep_2830, SagUGL, SpnUGL, SpyUGL, UGL, unsaturated glucuronyl hydrolase |
| EC Number |
3.2.1.180 |
| CAS编号 |
|
| Comments |
The enzyme releases 4-deoxy-4,5-didehydro?D-glucuronic acid or 4-deoxy-4,5-didehydro?L-iduronic acid from chondroitin disaccharides, hyaluronan disaccharides and heparin disaccharides and cleaves both glycosidic (1¡ú3) and (1¡ú4) bonds. It prefers the sulfated disaccharides to the unsulfated disaccharides. |
| Cofactor |
|
| History |
|
| Reactions |
Beta-D-4-deoxy-Delta(4)-GlcAp-(1->3)-beta-D-GalNAc6S + H(2)O = 5-dehydro- 4-deoxy-D-glucuronate + N-acetyl-beta-D-galactosamine-6-O-sulfate. |