| 英文名 |
very-long-chain 3-oxoacyl-CoA reductase |
| Example Structure |
 |
| 别名 |
3-ketoacyl-CoA reductase, beta-ketoacyl-CoA reductase, IFA38, KCR, KCR1, KCR2, KCR3, very-long-chain 3-ketoacyl-CoA reductase, very-long-chain beta-ketoacyl-CoA reductase, ybr159, YBR159w |
| EC Number |
1.1.1.330 |
| CAS编号 |
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| Comments |
The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs. The enzyme is active with substrates with chain length of C16 to C34, depending on the species. cf. EC 2.3.1.199, very-long-chain 3-oxoacyl-CoA synthase, EC 4.2.1.134, very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase, and EC 1.3.1.93, very-long-chain enoyl-CoA reductase. |
| Cofactor |
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| History |
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| Reactions |
A very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + Nadph. |
