| 英文名 |
vitamin-K-epoxide reductase (warfarin-insensitive) |
| Example Structure |
 |
| 别名 |
non-VKOR, reductase, vitamin K epoxide (warfarin-insensitive), vitamin K 2,3 epoxide reductase, vitamin K epoxide reductase, vitamin K epoxide reductase (warfarin-insensitive), vitamin K epoxide reductase-like1, vitamin KO reductase, VKOR, VKOR-like1, VKORC1L1, VKORL1 |
| EC Number |
1.17.4.5 |
| CAS编号 |
97089-80-0 |
| Comments |
Vitamin K 2,3-epoxide is reduced to 3-hydroxy- (and 2-hydroxy-) vitamin K by 1,4-dithiothreitol, which is oxidized to a disulfide. Not inhibited by warfarin [cf. EC 1.17.4.4, vitamin-K-epoxide reductase (warfarin-sensitive)]. |
| Cofactor |
|
| History |
|
| Reactions |
3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4- naphthoquinone + 1,4-dithiothreitol. |
