| 英文名 |
[Wnt protein] O-palmitoleoyl transferase |
| Example Structure |
![Example Structure of [Wnt protein] O-palmitoleoyl transferase EC#: 2.3.1.250](/wp-content/uploads/enzyme-structure/2.3.1.250.jpg) |
| 别名 |
CG6205, MG61, Mom-1, Mporc, mPorcD, PORC, PORCN, PPN, protein-serine O-palmitoleoyltransferase porcupine, Xporc |
| EC Number |
2.3.1.250 |
| CAS编号 |
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| Comments |
The enzyme, found in animals, modifies a specific serine residue in Wnt proteins, e.g. Ser209 in human Wnt3a and Ser224 in chicken WNT1 [2,3]. The enzyme can accept C13 to C16 fatty acids in vitro, but only (9Z)-hexadecenoate modification is observed in vivo [1]. cf. EC 3.1.1.98, [Wnt protein]-O-palmitoleoyl-L-serine hydrolase. |
| Cofactor |
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| History |
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| Reactions |
(9Z)-hexadec-9-enoyl-CoA + [Wnt]-L-serine = CoA + [Wnt]-O-(9Z)-hexadec-9- enoyl-L-serine. |
